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ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms

Zinc finger MYND-type-containing 10 (ZMYND10), a cytoplasmic protein expressed in ciliated cells, causes primary ciliary dyskinesia (PCD) when mutated; however, its function is poorly understood. Therefore, in this study, we examined the roles of ZMYND10 using Zmynd10(–/–)mice exhibiting typical PCD...

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Detalles Bibliográficos
Autores principales: Cho, Kyeong Jee, Noh, Shin Hye, Han, Soo Min, Choi, Won-Il, Kim, Hye-Youn, Yu, Seyoung, Lee, Joon Suk, Rim, John Hoon, Lee, Min Goo, Hildebrandt, Friedhelm, Gee, Heon Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895051/
https://www.ncbi.nlm.nih.gov/pubmed/29601588
http://dx.doi.org/10.1371/journal.pgen.1007316