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High-efficiency antibody discovery achieved with multiplexed microscopy

The analysis of secreted antibody from large and diverse populations of B cells in parallel at the clonal level can reveal desirable antibodies for diagnostic or therapeutic applications. By immobilizing B cells in microdroplets with particulate reporters, decoding and isolating them in a microscopy...

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Detalles Bibliográficos
Autores principales: Mettler Izquierdo, Shelley, Varela, Stephanie, Park, Minha, Collarini, Ellen J., Lu, Daniel, Pramanick, Shreya, Rucker, Joseph, Lopalco, Lucia, Etches, Rob, Harriman, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895110/
https://www.ncbi.nlm.nih.gov/pubmed/27107009
http://dx.doi.org/10.1093/jmicro/dfw014