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Joint nociceptor nerve activity and pain in an animal model of acute gout and its modulation by intra-articular hyaluronan

The mechanisms whereby deposition of monosodium urate (MSU) crystals in gout activates nociceptors to induce joint pain are incompletely understood. We tried to reproduce the signs of painful gouty arthritis, injecting into the knee joint of rats suspensions containing amorphous or triclinic, needle...

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Detalles Bibliográficos
Autores principales: Marcotti, Aida, Miralles, Ana, Dominguez, Eduardo, Pascual, Eliseo, Gomis, Ana, Belmonte, Carlos, de la Peña, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895116/
https://www.ncbi.nlm.nih.gov/pubmed/29319609
http://dx.doi.org/10.1097/j.pain.0000000000001137