Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials: A Simulation Study

BACKGROUND AND PURPOSE—: The utility-weighted modified Rankin Scale (UW-mRS) has been proposed as a new patient-centered primary outcome in stroke trials. We aimed to describe utility weights for the mRS health states and to evaluate the statistical efficiency of the UW-mRS to detect treatment effec...

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Detalles Bibliográficos
Autores principales: Dijkland, Simone A., Voormolen, Daphne C., Venema, Esmee, Roozenbeek, Bob, Polinder, Suzanne, Haagsma, Juanita A., Nieboer, Daan, Chalos, Vicky, Yoo, Albert J., Schreuders, Jennifer, van der Lugt, Aad, Majoie, Charles B.L.M., Roos, Yvo B.W.E.M., van Zwam, Wim H., van Oostenbrugge, Robert J., Steyerberg, Ewout W., Dippel, Diederik W.J., Lingsma, Hester F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895119/
https://www.ncbi.nlm.nih.gov/pubmed/29535271
http://dx.doi.org/10.1161/STROKEAHA.117.020194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895119/
https://www.ncbi.nlm.nih.gov/pubmed/29535271
http://dx.doi.org/10.1161/STROKEAHA.117.020194

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