HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation

OBJECTIVE: HIV-1 frequently adapts in response to immune pressure from cytotoxic T-lymphocytes (CTL). Many HIV-2 infected individuals have robust capsid-specific CTL responses associated with viral control. Despite this CTL pressure, adaptive changes in this key immunogenic HIV-2 protein have not pr...

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Detalles Bibliográficos
Autores principales: de Silva, Thushan I., Leligdowicz, Aleksandra, Carlson, Jonathan, Garcia-Knight, Miguel, Onyango, Clayton, Miller, Nicholas, Yindom, Louis-Marie, Hué, Stephane, Jaye, Assan, Dong, Tao, Cotten, Matthew, Rowland-Jones, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Basic Science: Concise Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895130/
https://www.ncbi.nlm.nih.gov/pubmed/29369160
http://dx.doi.org/10.1097/QAD.0000000000001753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895130/
https://www.ncbi.nlm.nih.gov/pubmed/29369160
http://dx.doi.org/10.1097/QAD.0000000000001753

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