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Preclinical Assessment of CAR T-Cell Therapy Targeting the Tumor Antigen 5T4 in Ovarian Cancer

Chimeric antigen receptor (CAR) T cells represent a novel targeted approach to overcome both quantitative and qualitative shortfalls of the host immune system relating to the detection and subsequent destruction of tumors. The identification of antigens expressed specifically on the surface of tumor...

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Detalles Bibliográficos
Autores principales: Owens, Gemma L., Sheard, Victoria E., Kalaitsidou, Milena, Blount, Daniel, Lad, Yatish, Cheadle, Eleanor J., Edmondson, Richard J., Kooner, Gurdeep, Gilham, David E., Harrop, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895166/
https://www.ncbi.nlm.nih.gov/pubmed/29239915
http://dx.doi.org/10.1097/CJI.0000000000000203