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Preclinical Assessment of CAR T-Cell Therapy Targeting the Tumor Antigen 5T4 in Ovarian Cancer
Chimeric antigen receptor (CAR) T cells represent a novel targeted approach to overcome both quantitative and qualitative shortfalls of the host immune system relating to the detection and subsequent destruction of tumors. The identification of antigens expressed specifically on the surface of tumor...
Autores principales: | Owens, Gemma L., Sheard, Victoria E., Kalaitsidou, Milena, Blount, Daniel, Lad, Yatish, Cheadle, Eleanor J., Edmondson, Richard J., Kooner, Gurdeep, Gilham, David E., Harrop, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895166/ https://www.ncbi.nlm.nih.gov/pubmed/29239915 http://dx.doi.org/10.1097/CJI.0000000000000203 |
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