Whole Recombinant Saccharomyces cerevisiae Yeast Expressing Ras Mutations as Treatment for Patients With Solid Tumors Bearing Ras Mutations: Results From a Phase 1 Trial

We are developing whole, heat-killed, recombinant Saccharomyces cerevisiae yeast, engineered to encode target proteins, which stimulate immune responses against malignant cells expressing those targets. This phase 1 trial, enrolling patients with advanced colorectal or pancreas cancer, was designed...

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Detalles Bibliográficos
Autores principales: Cohn, Allen, Morse, Michael A., O’Neil, Bert, Whiting, Samuel, Coeshott, Claire, Ferraro, John, Bellgrau, Donald, Apelian, David, Rodell, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Clinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895167/
https://www.ncbi.nlm.nih.gov/pubmed/29528991
http://dx.doi.org/10.1097/CJI.0000000000000219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895167/
https://www.ncbi.nlm.nih.gov/pubmed/29528991
http://dx.doi.org/10.1097/CJI.0000000000000219

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