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Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current

The assertion that large-diameter nerve fibers have low thresholds and small-diameter fibers have high thresholds in response to electrical stimulation has been held in a nearly axiomatic regard in the field of neuromodulation and neuroprosthetics. In contrast to the short pulses used to evoke actio...

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Detalles Bibliográficos
Autores principales: Yang, Fei, Anderson, Michael, He, Shaoqiu, Stephens, Kimberly, Zheng, Yu, Chen, Zhiyong, Raja, Srinivasa N., Aplin, Felix, Guan, Yun, Fridman, Gene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895440/
https://www.ncbi.nlm.nih.gov/pubmed/29651458
http://dx.doi.org/10.1126/sciadv.aaq1438