Sodium bicarbonate cotransporter NBCe2 gene variants increase sodium and bicarbonate transport in human renal proximal tubule cells

RATIONALE: Salt sensitivity of blood pressure affects >30% of the hypertensive and >15% of the normotensive population. Variants of the electrogenic sodium bicarbonate cotransporter NBCe2 gene, SLC4A5, are associated with increased blood pressure in several ethnic groups. SLC4A5 variants are a...

Descripción completa

Detalles Bibliográficos
Autores principales: Gildea, John J., Xu, Peng, Kemp, Brandon A., Carlson, Julia M., Tran, Hanh T., Bigler Wang, Dora, Langouët-Astrié, Christophe J., McGrath, Helen E., Carey, Robert M., Jose, Pedro A., Felder, Robin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895442/
https://www.ncbi.nlm.nih.gov/pubmed/29642240
http://dx.doi.org/10.1371/journal.pone.0189464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895442/
https://www.ncbi.nlm.nih.gov/pubmed/29642240
http://dx.doi.org/10.1371/journal.pone.0189464

Ejemplares similares