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Microglia activation mediated by toll-like receptor-4 impairs brain white matter tracts in rats

Microglia activation and white matter injury coexist after repeated episodes of mild brain trauma and ischemic stroke. Axon degeneration and demyelination can activate microglia; however, it is unclear whether early microglia activation can impair the function of white matter tracts and lead to inju...

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Detalles Bibliográficos
Autores principales: Yang, Xinglong, Zhang, Jingdong, Duan, Lian, Xiong, Huangui, Jiang, Yanping, Liang, Houcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895568/
https://www.ncbi.nlm.nih.gov/pubmed/29358565
http://dx.doi.org/10.7555/JBR.32.20170033