Distinctive roles of Rac1 and Rab29 in LRRK2 mediated membrane trafficking and neurite outgrowth

Parkinson’s disease (PD) associated leucine-rich repeat kinase 2 (LRRK2) mutants have shown pathogenic effects on variety of subcellular processes.Two small GTPases Rac1 and Rab29 have been indicated as possible downstream effectors participating in LRRK2 signaling but their detail mechanisms remain...

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Detalles Bibliográficos
Autores principales: Feng, Min, Hu, Xin, Li, Na, Hu, Fan, Chang, Fei, Xu, Hongfei, Liu, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895569/
https://www.ncbi.nlm.nih.gov/pubmed/29336357
http://dx.doi.org/10.7555/JBR.31.20170039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895569/
https://www.ncbi.nlm.nih.gov/pubmed/29336357
http://dx.doi.org/10.7555/JBR.31.20170039

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