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Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants

Ubiquitylation of histone H2B at lysine residue 120 (H2BK120ub) is a prominent histone posttranslational modification (PTM) associated with the actively transcribed genome. Although H2BK120ub triggers several critical downstream histone modification pathways and changes in chromatin structure, less...

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Detalles Bibliográficos
Autores principales: Wojcik, Felix, Dann, Geoffrey P., Beh, Leslie Y., Debelouchina, Galia T., Hofmann, Raphael, Muir, Tom W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895630/
https://www.ncbi.nlm.nih.gov/pubmed/29643390
http://dx.doi.org/10.1038/s41467-018-03895-5