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The Rapid Emergence of Tigecycline Resistance in bla(KPC–2) Harboring Klebsiella pneumoniae, as Mediated in Vivo by Mutation in tetA During Tigecycline Treatment

Tigecycline is one of the last resort treatments for carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. Tigecycline resistance often occurs during the clinical treatment of CRKP, yet its mechanism has still not been clearly elucidated. This study presents an analysis of a tigecycline resi...

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Detalles Bibliográficos
Autores principales: Du, Xiaoxing, He, Fang, Shi, Qiucheng, Zhao, Feng, Xu, Juan, Fu, Ying, Yu, Yunsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895649/
https://www.ncbi.nlm.nih.gov/pubmed/29675006
http://dx.doi.org/10.3389/fmicb.2018.00648