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Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis

In infants intolerant of enteral feeding because of intestinal disease, parenteral nutrition may be associated with cholestasis, which can progress to end-stage liver disease. Here we show the function of hepatic macrophages and phytosterols in parenteral nutrition-associated cholestasis (PNAC) path...

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Detalles Bibliográficos
Autores principales: El Kasmi, Karim C., Vue, Padade M., Anderson, Aimee L., Devereaux, Michael W., Ghosh, Swati, Balasubramaniyan, Natarajan, Fillon, Sophie A., Dahrenmoeller, Carola, Allawzi, Ayed, Woods, Crystal, McKenna, Sarah, Wright, Clyde J., Johnson, Linda, D’Alessandro, Angelo, Reisz, Julie A., Nozik-Grayck, Eva, Suchy, Frederick J., Sokol, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895696/
https://www.ncbi.nlm.nih.gov/pubmed/29643332
http://dx.doi.org/10.1038/s41467-018-03764-1