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Activation of the DnaK-ClpB Complex is Regulated by the Properties of the Bound Substrate
The chaperone ClpB in bacteria is responsible for the reactivation of aggregated proteins in collaboration with the DnaK system. Association of these chaperones at the aggregate surface stimulates ATP hydrolysis, which mediates substrate remodeling. However, a question that remains unanswered is whe...
Autores principales: | Fernández-Higuero, Jose Angel, Aguado, Alejandra, Perales-Calvo, Judit, Moro, Fernando, Muga, Arturo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895705/ https://www.ncbi.nlm.nih.gov/pubmed/29643454 http://dx.doi.org/10.1038/s41598-018-24140-5 |
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