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Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle
Self-assembling proteins are critical to biological systems and industrial technologies, but predicting how mutations affect self-assembly remains a significant challenge. Here, we report a technique, termed SyMAPS (Systematic Mutation and Assembled Particle Selection), that can be used to character...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895741/ https://www.ncbi.nlm.nih.gov/pubmed/29643335 http://dx.doi.org/10.1038/s41467-018-03783-y |