Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA

Whilst 5-methylcytosine (5mC) is a major epigenetic mark in the nuclear DNA in mammals, whether or not mitochondrial DNA (mtDNA) receives 5mC modification remains controversial. Herein, we exhaustively analysed mouse mtDNA using three methods that are based upon different principles for detecting 5m...

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Detalles Bibliográficos
Autores principales: Matsuda, Shigeru, Yasukawa, Takehiro, Sakaguchi, Yuriko, Ichiyanagi, Kenji, Unoki, Motoko, Gotoh, Kazuhito, Fukuda, Kei, Sasaki, Hiroyuki, Suzuki, Tsutomu, Kang, Dongchon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895755/
https://www.ncbi.nlm.nih.gov/pubmed/29643477
http://dx.doi.org/10.1038/s41598-018-24251-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895755/
https://www.ncbi.nlm.nih.gov/pubmed/29643477
http://dx.doi.org/10.1038/s41598-018-24251-z

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