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Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA
Whilst 5-methylcytosine (5mC) is a major epigenetic mark in the nuclear DNA in mammals, whether or not mitochondrial DNA (mtDNA) receives 5mC modification remains controversial. Herein, we exhaustively analysed mouse mtDNA using three methods that are based upon different principles for detecting 5m...
Autores principales: | Matsuda, Shigeru, Yasukawa, Takehiro, Sakaguchi, Yuriko, Ichiyanagi, Kenji, Unoki, Motoko, Gotoh, Kazuhito, Fukuda, Kei, Sasaki, Hiroyuki, Suzuki, Tsutomu, Kang, Dongchon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895755/ https://www.ncbi.nlm.nih.gov/pubmed/29643477 http://dx.doi.org/10.1038/s41598-018-24251-z |
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