Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via epigenetic changes in mesenchymal stromal/stem cells

Human mesenchymal stromal/stem cells (hMSCs) emerged as a promising therapeutic tool for ischemic disorders, due to their ability to regenerate damaged tissues, promote angiogenesis and reduce inflammation, leading to encouraging, but still limited results. The outcomes in clinical trials exploring...

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Detalles Bibliográficos
Autores principales: Cuomo, Francesca, Coppola, Antonietta, Botti, Chiara, Maione, Ciro, Forte, Amalia, Scisciola, Lucia, Liguori, Giuseppina, Caiafa, Ilaria, Ursini, Matilde Valeria, Galderisi, Umberto, Cipollaro, Marilena, Altucci, Lucia, Cobellis, Gilda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895792/
https://www.ncbi.nlm.nih.gov/pubmed/29643458
http://dx.doi.org/10.1038/s41598-018-24221-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895792/
https://www.ncbi.nlm.nih.gov/pubmed/29643458
http://dx.doi.org/10.1038/s41598-018-24221-5

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