Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs

Multicellular organisms consist of multiple cell types. The identity of these cells is primarily maintained by cell-type-specific gene expression programs; however, mechanisms that suppress these programs are poorly defined. Here we show that serum response factor (Srf), a transcription factor that...

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Detalles Bibliográficos
Autores principales: Ikeda, Takashi, Hikichi, Takafusa, Miura, Hisashi, Shibata, Hirofumi, Mitsunaga, Kanae, Yamada, Yosuke, Woltjen, Knut, Miyamoto, Kei, Hiratani, Ichiro, Yamada, Yasuhiro, Hotta, Akitsu, Yamamoto, Takuya, Okita, Keisuke, Masui, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895821/
https://www.ncbi.nlm.nih.gov/pubmed/29643333
http://dx.doi.org/10.1038/s41467-018-03748-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895821/
https://www.ncbi.nlm.nih.gov/pubmed/29643333
http://dx.doi.org/10.1038/s41467-018-03748-1

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