Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections

Host immunity exerts strong selective pressure on pathogens. Population-level genetic analysis can identify signatures of this selection, but these signatures reflect the net selective effect of all hosts and vectors in a population. In contrast, analysis of pathogen diversity within hosts provides...

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Detalles Bibliográficos
Autores principales: Early, Angela M., Lievens, Marc, MacInnis, Bronwyn L., Ockenhouse, Christian F., Volkman, Sarah K., Adjei, Samuel, Agbenyega, Tsiri, Ansong, Daniel, Gondi, Stacey, Greenwood, Brian, Hamel, Mary, Odero, Chris, Otieno, Kephas, Otieno, Walter, Owusu-Agyei, Seth, Asante, Kwaku Poku, Sorgho, Hermann, Tina, Lucas, Tinto, Halidou, Valea, Innocent, Wirth, Dyann F., Neafsey, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895824/
https://www.ncbi.nlm.nih.gov/pubmed/29643376
http://dx.doi.org/10.1038/s41467-018-03807-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895824/
https://www.ncbi.nlm.nih.gov/pubmed/29643376
http://dx.doi.org/10.1038/s41467-018-03807-7

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