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Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the huntingtin (HTT) gene which results in progressive neurodegeneration in the striatum, cortex, and eventually most brain areas. Despite being a monogenic disorder, environmental factors influence H...

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Detalles Bibliográficos
Autores principales: Novati, Arianna, Hentrich, Thomas, Wassouf, Zinah, Weber, Jonasz J., Yu-Taeger, Libo, Déglon, Nicole, Nguyen, Huu Phuc, Schulze-Hentrich, Julia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895842/
https://www.ncbi.nlm.nih.gov/pubmed/29643462
http://dx.doi.org/10.1038/s41598-018-24243-z