In Vitro Functional Characterization of GET73 as Possible Negative Allosteric Modulator of Metabotropic Glutamate Receptor 5

The present study was aimed to further characterize the pharmacological profile of N-[4-(trifluoromethyl) benzyl]-4-methoxybutyramide (GET73), a putative negative allosteric modulator (NAM) of metabotropic glutamate subtype 5 receptor (mGluR5) under development as a novel medication for the treatmen...

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Detalles Bibliográficos
Autores principales: Beggiato, Sarah, Borelli, Andrea C., Tomasini, Maria C., Castelli, M. Paola, Pintori, Nicholas, Cacciaglia, Roberto, Loche, Antonella, Ferraro, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895880/
https://www.ncbi.nlm.nih.gov/pubmed/29674969
http://dx.doi.org/10.3389/fphar.2018.00327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895880/
https://www.ncbi.nlm.nih.gov/pubmed/29674969
http://dx.doi.org/10.3389/fphar.2018.00327

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