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Effects of a phosphocitrate analogue on osteophyte, subchondral bone advance, and bone marrow lesions in Hartley guinea pigs

OBJECTIVES: The objectives of this study were: 1) to examine osteophyte formation, subchondral bone advance, and bone marrow lesions (BMLs) in osteoarthritis (OA)-prone Hartley guinea pigs; and 2) to assess the disease-modifying activity of an orally administered phosphocitrate ‘analogue’, Carolinas...

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Detalles Bibliográficos
Autores principales: Sun, Y., Kiraly, A. J., Sun, A. R., Cox, M., Mauerhan, D. R., Hanley, E. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895945/
https://www.ncbi.nlm.nih.gov/pubmed/29682281
http://dx.doi.org/10.1302/2046-3758.72.BJR-2017-0253