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Epithelial to mesenchymal transition induces stem cell like phenotype in renal cell carcinoma cells

BACKGROUND: Metastatic dissemination of solid tumors is often initiated by reactivation of an embryonic development program, epithelial-to-mesenchymal-transition (EMT). EMT has been associated with acquiring invasiveness and resistance to conventional therapies. However, the precise role of EMT duri...

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Detalles Bibliográficos
Autores principales: Singla, Mamta, Kumar, Ajay, Bal, Amanjit, Sarkar, Subhendu, Bhattacharyya, Shalmoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896088/
https://www.ncbi.nlm.nih.gov/pubmed/29681769
http://dx.doi.org/10.1186/s12935-018-0555-6