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SP1-induced upregulation of lncRNA SPRY4-IT1 exerts oncogenic properties by scaffolding EZH2/LSD1/DNMT1 and sponging miR-101-3p in cholangiocarcinoma

BACKGROUND: Accumulating evidence has indicated that long non-coding RNAs (lncRNAs) behave as a novel class of transcription products during multiple cancer processes. However, the mechanisms responsible for their alteration in cholangiocarcinoma (CCA) are not fully understood. METHODS: The expressi...

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Detalles Bibliográficos
Autores principales: Xu, Yi, Yao, Yue, Jiang, Xingming, Zhong, Xiangyu, Wang, Zhidong, Li, Chunlong, Kang, Pengcheng, Leng, Kaiming, Ji, Daolin, Li, Zhenglong, Huang, Lining, Qin, Wei, Cui, Yunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896100/
https://www.ncbi.nlm.nih.gov/pubmed/29642935
http://dx.doi.org/10.1186/s13046-018-0747-x