Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice

BACKGROUND: Neuroinflammation plays an important role in the pathogenesis of intracerebral hemorrhage (ICH)-induced secondary brain injury. Activation of melanocortin receptor 4 (MC4R) has been shown to elicit anti-inflammatory effects in many diseases. The objective of this study was to explore the...

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Detalles Bibliográficos
Autores principales: Chen, Shengpan, Zhao, Lianhua, Sherchan, Prativa, Ding, Yan, Yu, Jing, Nowrangi, Derek, Tang, Jiping, Xia, Ying, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896146/
https://www.ncbi.nlm.nih.gov/pubmed/29642894
http://dx.doi.org/10.1186/s12974-018-1140-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896146/
https://www.ncbi.nlm.nih.gov/pubmed/29642894
http://dx.doi.org/10.1186/s12974-018-1140-6

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