Cargando…

Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice

BACKGROUND: Neuroinflammation plays an important role in the pathogenesis of intracerebral hemorrhage (ICH)-induced secondary brain injury. Activation of melanocortin receptor 4 (MC4R) has been shown to elicit anti-inflammatory effects in many diseases. The objective of this study was to explore the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Shengpan, Zhao, Lianhua, Sherchan, Prativa, Ding, Yan, Yu, Jing, Nowrangi, Derek, Tang, Jiping, Xia, Ying, Zhang, John H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896146/ https://www.ncbi.nlm.nih.gov/pubmed/29642894 http://dx.doi.org/10.1186/s12974-018-1140-6

Ejemplares similares

Recombinant CTRP9 administration attenuates neuroinflammation via activating adiponectin receptor 1 after intracerebral hemorrhage in mice
por: Zhao, Lianhua, et al.
Publicado: (2018)

TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice
por: Chen, Shengpan, et al.
Publicado: (2020)

Administration of rCTRP9 Attenuates Neuronal Apoptosis Through AdipoR1/PI3K/Akt Signaling Pathway after ICH in Mice
por: Zhao, Lianhua, et al.
Publicado: (2019)

Orexin A alleviates neuroinflammation via OXR2/CaMKKβ/AMPK signaling pathway after ICH in mice
por: Li, Tao, et al.
Publicado: (2020)

PA3225 Is a Transcriptional Repressor of Antibiotic Resistance Mechanisms in Pseudomonas aeruginosa
por: Hall, Clayton W., et al.
Publicado: (2017)

DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage
por: Xu, Yang, et al.
Publicado: (2020)

The Activation of Phosphatidylserine/CD36/TGF-β1 Pathway prior to Surgical Brain Injury Attenuates Neuroinflammation in Rats
por: Huang, Lei, et al.
Publicado: (2020)

Activation of Frizzled-7 attenuates blood–brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice
por: He, Wei, et al.
Publicado: (2021)

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma
por: Pua, Lesley Jia Wei, et al.
Publicado: (2022)

Inhibition of Aryl Hydrocarbon Receptor Attenuates Hyperglycemia‐Induced Hematoma Expansion in an Intracerebral Hemorrhage Mouse Model
por: Ren, Reng, et al.
Publicado: (2021)

Data on the phosphorylation of p38MAPK and JNK induced by chlorpyrifos in Drosophila melanogaster
por: Batista, J.E.S., et al.
Publicado: (2016)

Autophagy & Phagocytosis in Neurological Disorders and their Possible Cross-talk
por: Li, Gaigai, et al.
Publicado: (2021)

Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice
por: Deng, Shuixiang, et al.
Publicado: (2021)

A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
por: Liu, Xin, et al.
Publicado: (2016)

Aprepitant Inhibits JNK and p38/MAPK to Attenuate Inflammation and Suppresses Inflammatory Pain
por: Yang, Yang, et al.
Publicado: (2022)

Acute Treatment With Gleevec Does Not Promote Early Vascular Recovery Following Intracerebral Hemorrhage in Adult Male Rats
por: Abbas, Mohammed, et al.
Publicado: (2020)

Neuroinflammation after intracerebral hemorrhage
por: Mracsko, Eva, et al.
Publicado: (2014)

Cholesterol biosynthesis inhibitor RO 48-8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway
por: Ding, Zhen, et al.
Publicado: (2021)

The activation of p38MAPK and JNK pathways in bovine herpesvirus 1 infected MDBK cells
por: Zhu, Liqian, et al.
Publicado: (2016)

Neurotrophin3 promotes hepatocellular carcinoma apoptosis through the JNK and P38 MAPK pathways
por: Yang, Zhangshuo, et al.
Publicado: (2022)

Inhibition of lysophosphatidic acid receptor 1 relieves PMN recruitment in CNS via LPA1/TSP1/CXCR2 pathway and alleviates disruption on blood-brain barrier following intracerebral haemorrhage in mice
por: Gao, Ling, et al.
Publicado: (2023)

Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in intracerebral hemorrhage mice
por: Wang, Tian, et al.
Publicado: (2018)

Nonthermal Plasma Induces Apoptosis in ATC Cells: Involvement of JNK and p38 MAPK-Dependent ROS
por: Lee, Sei Young, et al.
Publicado: (2014)

Bavachinin Induces Oxidative Damage in HepaRG Cells through p38/JNK MAPK Pathways
por: Wang, Shan, et al.
Publicado: (2018)

Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway
por: Yang, Xiaorong, et al.
Publicado: (2018)

N-Hydroxycinnamide Derivatives of Osthole Ameliorate Hyperglycemia through Activation of AMPK and p38 MAPK
por: Lee, Wei-Hwa, et al.
Publicado: (2015)

Sanguinarine Attenuates Neuropathic Pain by Inhibiting P38 MAPK Activated Neuroinflammation in Rat Model
por: Yu, Chao, et al.
Publicado: (2020)

Inhibition of HDAC6 alleviating lipopolysaccharide-induced p38MAPK phosphorylation and neuroinflammation in mice
por: Song, Yuanjian, et al.
Publicado: (2019)

Melanocortins, Melanocortin Receptors and Multiple Sclerosis
por: Lisak, Robert P., et al.
Publicado: (2017)

Recombinant Slit2 Reduces Surgical Brain Injury Induced Blood Brain Barrier Disruption via Robo4 Dependent Rac1 Activation in a Rodent Model
por: Sherchan, Prativa, et al.
Publicado: (2017)

Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation
por: Lee, Tae-Hoon, et al.
Publicado: (2014)

Antitumor effect of Quercetin on Y79 retinoblastoma cells via activation of JNK and p38 MAPK pathways
por: Liu, Haojie, et al.
Publicado: (2017)

High glucose promotes annulus fibrosus cell apoptosis through activating the JNK and p38 MAPK pathways
por: Shan, Lizhen, et al.
Publicado: (2019)

A sestrin-dependent Erk/Jnk/p38 MAPK activation complex inhibits immunity during ageing
por: Lanna, Alessio, et al.
Publicado: (2017)

Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
por: Chen, Xueran, et al.
Publicado: (2020)

Recombinant Slit2 suppresses neuroinflammation and Cdc42-mediated brain infiltration of peripheral immune cells via Robo1–srGAP1 pathway in a rat model of germinal matrix hemorrhage
por: Li, Qian, et al.
Publicado: (2023)

Naja sputatrix Venom Preconditioning Attenuates Neuroinflammation in a Rat Model of Surgical Brain Injury via PLA2/5-LOX/LTB4 Cascade Activation
por: Wang, Yuechun, et al.
Publicado: (2017)

CD38 in Neurodegeneration and Neuroinflammation
por: Guerreiro, Serge, et al.
Publicado: (2020)

DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation
por: Zhang, Long-Qing, et al.
Publicado: (2022)

Involvement of AMPKα and MAPK-ERK/-JNK Signals in Docetaxel-Induced Human Tongue Squamous Cell Carcinoma Cell Apoptosis
por: Su, Chin-Chuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ic6neu4k0sp46vpo14c6bsg9cd