Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways

In Alzheimer’s disease, neurofibrillary tangle pathology appears to spread along neuronal connections, proposed to be mediated by the release and uptake of abnormal, disease-specific forms of microtubule-binding protein tau MAPT. It is currently unclear whether transfer of tau between neurons is a t...

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Detalles Bibliográficos
Autores principales: Evans, Lewis D., Wassmer, Thomas, Fraser, Graham, Smith, James, Perkinton, Michael, Billinton, Andrew, Livesey, Frederick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896171/
https://www.ncbi.nlm.nih.gov/pubmed/29590627
http://dx.doi.org/10.1016/j.celrep.2018.03.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896171/
https://www.ncbi.nlm.nih.gov/pubmed/29590627
http://dx.doi.org/10.1016/j.celrep.2018.03.021

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