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The Murine Natural Cytotoxic Receptor NKp46/NCR1 Controls TRAIL Protein Expression in NK Cells and ILC1s

TRAIL is an apoptosis-inducing ligand constitutively expressed on liver-resident type 1 innate lymphoid cells (ILC1s) and a subset of natural killer (NK) cells, where it contributes to NK cell anti-tumor, anti-viral, and immunoregulatory functions. However, the intrinsic pathways involved in TRAIL e...

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Detalles Bibliográficos
Autores principales: Sheppard, Sam, Schuster, Iona S., Andoniou, Christopher E., Cocita, Clement, Adejumo, Thomas, Kung, Sam K.P., Sun, Joseph C., Degli-Esposti, Mariapia A., Guerra, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896200/
https://www.ncbi.nlm.nih.gov/pubmed/29590608
http://dx.doi.org/10.1016/j.celrep.2018.03.023