An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic β-Cell Injury, Response, and Prevention

It is well known that a chronic state of elevated reactive oxygen species (ROS) in pancreatic β-cells impairs their ability to release insulin in response to elevated plasma glucose. Moreover, at its extreme, unmitigated ROS drives regulated cell death. This dysfunctional state of ROS buildup can re...

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Detalles Bibliográficos
Autores principales: Kulkarni, Abhishek A., Conteh, Abass M., Sorrell, Cody A., Mirmira, Anjali, Tersey, Sarah A., Mirmira, Raghavendra G., Linnemann, Amelia K., Anderson, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896207/
https://www.ncbi.nlm.nih.gov/pubmed/29785241
http://dx.doi.org/10.1155/2018/1324739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896207/
https://www.ncbi.nlm.nih.gov/pubmed/29785241
http://dx.doi.org/10.1155/2018/1324739

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