More than Just an Immunosuppressant: The Emerging Role of FTY720 as a Novel Inducer of ROS and Apoptosis

Fingolimod hydrochloride (FTY720) is a first-in-class of sphingosine-1-phosphate (S1P) receptor modulator approved to treat multiple sclerosis by its phosphorylated form (FTY720-P). Recently, a novel role of FTY720 as a potential anticancer drug has emerged. One of the anticancer mechanisms of FTY72...

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Detalles Bibliográficos
Autores principales: Takasaki, Teruaki, Hagihara, Kanako, Satoh, Ryosuke, Sugiura, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896217/
https://www.ncbi.nlm.nih.gov/pubmed/29785244
http://dx.doi.org/10.1155/2018/4397159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896217/
https://www.ncbi.nlm.nih.gov/pubmed/29785244
http://dx.doi.org/10.1155/2018/4397159

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