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Leishmania infantum Lipophosphoglycan-Deficient Mutants: A Tool to Study Host Cell-Parasite Interplay

Lipophosphoglycan (LPG) is the major surface glycoconjugate of metacyclic Leishmania promastigotes and is associated with virulence in various species of this parasite. Here, we generated a LPG-deficient mutant of Leishmania infantum, the foremost etiologic agent of visceral leishmaniasis in Brazil....

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Detalles Bibliográficos
Autores principales: Lázaro-Souza, Milena, Matte, Christine, Lima, Jonilson B., Arango Duque, Guillermo, Quintela-Carvalho, Graziele, de Carvalho Vivarini, Áislan, Moura-Pontes, Sara, Figueira, Cláudio P., Jesus-Santos, Flávio H., Gazos Lopes, Ulisses, Farias, Leonardo P., Araújo-Santos, Théo, Descoteaux, Albert, Borges, Valéria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896263/
https://www.ncbi.nlm.nih.gov/pubmed/29675001
http://dx.doi.org/10.3389/fmicb.2018.00626