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Chiral auxiliary recycling in continuous flow: automated recovery and reuse of Oppolzer's sultam

The telescoping of a three-stage, chiral auxiliary-mediated transformation in flow is described, including continuous separation of the product and auxiliary. The auxiliary can either be collected for later reuse, or directly fed back to the beginning of the process for recycling in real time, enabl...

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Detalles Bibliográficos
Autores principales: Sullivan, R. J., Newman, S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896371/
https://www.ncbi.nlm.nih.gov/pubmed/29719686
http://dx.doi.org/10.1039/c7sc05192a