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Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes

Cysteine cathepsins normally function in the lysosomal degradation system where they are critical for the maintenance of cellular homeostasis and the MHC II immune response, and have been found to have major roles in several diseases and in tumor progression. Selective visualization of individual pr...

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Detalles Bibliográficos
Autores principales: Poreba, Marcin, Rut, Wioletta, Vizovisek, Matej, Groborz, Katarzyna, Kasperkiewicz, Paulina, Finlay, Darren, Vuori, Kristiina, Turk, Dusan, Turk, Boris, Salvesen, Guy S., Drag, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896380/
https://www.ncbi.nlm.nih.gov/pubmed/29719685
http://dx.doi.org/10.1039/c7sc04303a