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Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes
Cysteine cathepsins normally function in the lysosomal degradation system where they are critical for the maintenance of cellular homeostasis and the MHC II immune response, and have been found to have major roles in several diseases and in tumor progression. Selective visualization of individual pr...
Autores principales: | Poreba, Marcin, Rut, Wioletta, Vizovisek, Matej, Groborz, Katarzyna, Kasperkiewicz, Paulina, Finlay, Darren, Vuori, Kristiina, Turk, Dusan, Turk, Boris, Salvesen, Guy S., Drag, Marcin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896380/ https://www.ncbi.nlm.nih.gov/pubmed/29719685 http://dx.doi.org/10.1039/c7sc04303a |
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