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Chemoprevention in Patients with Peutz‐Jeghers Syndrome: Lessons Learned

LESSONS LEARNED. Motivating patients to enroll in chemopreventive studies is challenging. Chemoprevention with toxic drugs is not feasible. BACKGROUND. LKB1 mutations are the underlying genetic abnormality causing Peutz‐Jeghers syndrome (PJS) and are a potential target for everolimus. In this phase...

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Detalles Bibliográficos
Autores principales: de Brabander, Justin, Eskens, Ferry A.L.M., Korsse, Susanne E., Dekker, Evelien, Dewint, Pieter, van Leerdam, Monique E., van Eeden, Susanne, Klümpen, Heinz‐Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896716/
https://www.ncbi.nlm.nih.gov/pubmed/29371475
http://dx.doi.org/10.1634/theoncologist.2017-0682