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Chemoprevention in Patients with Peutz‐Jeghers Syndrome: Lessons Learned
LESSONS LEARNED. Motivating patients to enroll in chemopreventive studies is challenging. Chemoprevention with toxic drugs is not feasible. BACKGROUND. LKB1 mutations are the underlying genetic abnormality causing Peutz‐Jeghers syndrome (PJS) and are a potential target for everolimus. In this phase...
Autores principales: | de Brabander, Justin, Eskens, Ferry A.L.M., Korsse, Susanne E., Dekker, Evelien, Dewint, Pieter, van Leerdam, Monique E., van Eeden, Susanne, Klümpen, Heinz‐Josef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AlphaMed Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896716/ https://www.ncbi.nlm.nih.gov/pubmed/29371475 http://dx.doi.org/10.1634/theoncologist.2017-0682 |
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