Microenvironmental control of breast cancer subtype elicited by paracrine platelet derived growth factor-CC signaling

Breast tumors of the basal-like, hormone receptor-negative, subtype remain an unmet clinical challenge, as patients exhibit a high rate of recurrence and poor survival. Co-evolution of the malignant mammary epithelium and its underlying stroma instigates cancer-associated fibroblasts (CAFs) to endor...

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Detalles Bibliográficos
Autores principales: Roswall, Pernilla, Bocci, Matteo, Bartoschek, Michael, Li, Hong, Kristiansen, Glen, Jansson, Sara, Lehn, Sophie, Sjölund, Jonas, Reid, Steven, Larsson, Christer, Eriksson, Pontus, Anderberg, Charlotte, Cortez, Eliane, Saal, Lao H, Orsmark-Pietras, Christina, Cordero, Eugenia, Haller, B Kristian, Häkkinen, Jari, Burvenich, Ingrid JG, Lim, Elgene, Orimo, Akira, Höglund, Mattias, Rydén, Lisa, Moch, Holger, Scott, Andrew M, Eriksson, Ulf, Pietras, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896729/
https://www.ncbi.nlm.nih.gov/pubmed/29529015
http://dx.doi.org/10.1038/nm.4494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896729/
https://www.ncbi.nlm.nih.gov/pubmed/29529015
http://dx.doi.org/10.1038/nm.4494

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