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Microenvironmental control of breast cancer subtype elicited by paracrine platelet derived growth factor-CC signaling
Breast tumors of the basal-like, hormone receptor-negative, subtype remain an unmet clinical challenge, as patients exhibit a high rate of recurrence and poor survival. Co-evolution of the malignant mammary epithelium and its underlying stroma instigates cancer-associated fibroblasts (CAFs) to endor...
Autores principales: | Roswall, Pernilla, Bocci, Matteo, Bartoschek, Michael, Li, Hong, Kristiansen, Glen, Jansson, Sara, Lehn, Sophie, Sjölund, Jonas, Reid, Steven, Larsson, Christer, Eriksson, Pontus, Anderberg, Charlotte, Cortez, Eliane, Saal, Lao H, Orsmark-Pietras, Christina, Cordero, Eugenia, Haller, B Kristian, Häkkinen, Jari, Burvenich, Ingrid JG, Lim, Elgene, Orimo, Akira, Höglund, Mattias, Rydén, Lisa, Moch, Holger, Scott, Andrew M, Eriksson, Ulf, Pietras, Kristian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896729/ https://www.ncbi.nlm.nih.gov/pubmed/29529015 http://dx.doi.org/10.1038/nm.4494 |
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