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Bronchoalveolar lavage (BAL) cells in idiopathic pulmonary fibrosis express a complex pro-inflammatory, pro-repair, angiogenic activation pattern, likely associated with macrophage iron accumulation

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease of unknown cause characterized by alveolar epithelial damage, patchy interstitial fibrosis and diffuse microvascular abnormalities. In IPF, alveolar clustering of iron-laden alveolar macrophages—a common sign of microhemorrhage, has been...

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Detalles Bibliográficos
Autores principales: Lee, Jungnam, Arisi, Ivan, Puxeddu, Ermanno, Mramba, Lazarus K., Amicosante, Massimo, Swaisgood, Carmen M., Pallante, Marco, Brantly, Mark L., Sköld, C. Magnus, Saltini, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896901/
https://www.ncbi.nlm.nih.gov/pubmed/29649237
http://dx.doi.org/10.1371/journal.pone.0194803