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Bronchoalveolar lavage (BAL) cells in idiopathic pulmonary fibrosis express a complex pro-inflammatory, pro-repair, angiogenic activation pattern, likely associated with macrophage iron accumulation
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease of unknown cause characterized by alveolar epithelial damage, patchy interstitial fibrosis and diffuse microvascular abnormalities. In IPF, alveolar clustering of iron-laden alveolar macrophages—a common sign of microhemorrhage, has been...
Autores principales: | Lee, Jungnam, Arisi, Ivan, Puxeddu, Ermanno, Mramba, Lazarus K., Amicosante, Massimo, Swaisgood, Carmen M., Pallante, Marco, Brantly, Mark L., Sköld, C. Magnus, Saltini, Cesare |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896901/ https://www.ncbi.nlm.nih.gov/pubmed/29649237 http://dx.doi.org/10.1371/journal.pone.0194803 |
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