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Commonly used trafficking blocks disrupt ARF1 activation and the localization and function of specific Golgi proteins

ADP-ribosylation factor (ARF) proteins are key regulators of the secretory pathway. ARF1, through interacting with its effectors, regulates protein trafficking by facilitating numerous events at the Golgi. One unique ARF1 effector is golgin-160, which promotes the trafficking of only a specific subs...

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Detalles Bibliográficos
Autores principales: Gilbert, Catherine E., Sztul, Elizabeth, Machamer, Carolyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896932/
https://www.ncbi.nlm.nih.gov/pubmed/29467256
http://dx.doi.org/10.1091/mbc.E17-11-0622