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Dendritic spikes in hippocampal granule cells are necessary for long-term potentiation at the perforant path synapse

Long-term potentiation (LTP) of synaptic responses is essential for hippocampal memory function. Perforant-path (PP) synapses on hippocampal granule cells (GCs) contribute to the formation of associative memories, which are considered the cellular correlates of memory engrams. However, the mechanism...

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Detalles Bibliográficos
Autores principales: Kim, Sooyun, Kim, Yoonsub, Lee, Suk-Ho, Ho, Won-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896953/
https://www.ncbi.nlm.nih.gov/pubmed/29578411
http://dx.doi.org/10.7554/eLife.35269