A low dose lipid infusion is sufficient to induce insulin resistance and a pro-inflammatory response in human subjects

OBJECTIVE: The root cause behind the low-grade inflammatory state seen in insulin resistant (obesity and type 2 diabetes) states is unclear. Insulin resistant subjects have elevations in plasma free fatty acids (FFA), which are ligands for the pro-inflammatory toll-like receptor (TLR)4 pathway. We t...

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Detalles Bibliográficos
Autores principales: Liang, Hanyu, Lum, Helen, Alvarez, Andrea, Garduno-Garcia, Jose de Jesus, Daniel, Benjamin J., Musi, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897027/
https://www.ncbi.nlm.nih.gov/pubmed/29649324
http://dx.doi.org/10.1371/journal.pone.0195810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897027/
https://www.ncbi.nlm.nih.gov/pubmed/29649324
http://dx.doi.org/10.1371/journal.pone.0195810

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