A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses

Human GWAS of obesity have been successful in identifying loci associated with adiposity, but for the most part, these are non-coding SNPs whose function, or even whose gene of action, is unknown. To help identify the genes on which these human BMI loci may be operating, we conducted a high throughp...

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Detalles Bibliográficos
Autores principales: Baranski, Thomas J., Kraja, Aldi T., Fink, Jill L., Feitosa, Mary, Lenzini, Petra A., Borecki, Ingrid B., Liu, Ching-Ti, Cupples, L. Adrienne, North, Kari E., Province, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897035/
https://www.ncbi.nlm.nih.gov/pubmed/29608557
http://dx.doi.org/10.1371/journal.pgen.1007222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897035/
https://www.ncbi.nlm.nih.gov/pubmed/29608557
http://dx.doi.org/10.1371/journal.pgen.1007222

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