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Combining Intra-Tumoral Treg Depletion with Androgen Deprivation Therapy (ADT): Pre-Clinical Activity in the Myc-CaP Model

INTRODUCTION: Immune checkpoint blockade has shown promising anti-tumor activity against a variety of tumor types. However, responses in castration-resistant prostate cancer remain relatively rare - potentially due to low baseline levels of infiltration. Using an immunocompetent cMyc-driven model (M...

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Detalles Bibliográficos
Autores principales: Shen, Ying-Chun, Ghasemzadeh, Ali, Kochel, Christina M., Nirschl, Thomas R., Francica, Brian J., Lopez-Bujanda, Zoila A., Carrera Haro, Maria A., Tam, Ada, Anders, Robert A., Selby, Mark J., Korman, Alan J., Drake, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897134/
https://www.ncbi.nlm.nih.gov/pubmed/29203894
http://dx.doi.org/10.1038/s41391-017-0013-x