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Synthesis and preclinical evaluation of novel (18)F-labeled Glu-urea-Glu-based PSMA inhibitors for prostate cancer imaging: a comparison with (18)F-DCFPyl and (18)F-PSMA-1007

BACKGROUND: Due to its high and consistent expression in prostate cancer (PCa), the prostate-specific membrane antigen (PSMA) represents an ideal target for molecular imaging and targeted therapy using highly specific radiolabeled PSMA ligands. To address the continuously growing clinical demand for...

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Detalles Bibliográficos
Autores principales: Robu, Stephanie, Schmidt, Alexander, Eiber, Matthias, Schottelius, Margret, Günther, Thomas, Hooshyar Yousefi, Behrooz, Schwaiger, Markus, Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897267/
https://www.ncbi.nlm.nih.gov/pubmed/29651565
http://dx.doi.org/10.1186/s13550-018-0382-8