Cargando…

Compositional characteristics of human peripheral TRBV pseudogene rearrangements

The diversity of the T cell receptor (TCR) complementarity determining region 3 (CDR3) repertoire is the result of random combinations, insertions and deletions during recombination of the germline V, D and J gene fragments. During evolution, some human TCR beta chain variable (TRBV) pseudogenes hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Bin, Ma, Long, He, Xiaoyan, Wu, Peipei, Wang, Peng, Wang, Xiaomei, Ma, Rui, Yao, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897323/
https://www.ncbi.nlm.nih.gov/pubmed/29651132
http://dx.doi.org/10.1038/s41598-018-24367-2